Welcome to Yokota Skeletal Research Lab in the Department of Biomedical Engineering at Indiana University Purdue University Indianapolis (IUPUI).  Our lab conducts basic and translational research using multidisciplinary approaches, including mathematical and computational modeling, molecular and cellular characterization, and pre-clinical evaluation using animal models.  We investigate regulatory mechanisms and develop effective treatment for bone and joint disorders such as osteoporosis, osteogenesis imperfecta, osteoarthritis, rheumatoid arthritis, as well as for breast cancer and bone metastasis.


We are grateful for the following sponsors: National Institutes of Health (NIAMS and NIGMS), Department of Defense, 100 Voices of Hope, and State of Indiana.